In organic chemistry, phosphonates or phosphonic acids are organophosphorus compounds containing C−PO(OR)2 groups (where R = alkyl, aryl, or just hydrogen). Phosphonic acids, typically handled as salts, are generally nonvolatile solids that are poorly soluble in organic solvents, but soluble in water and … See more Phosphonates feature tetrahedral phosphorus centers. They are structurally closely related to (and often prepared from) phosphorous acid. Phosphonate salts are the result of deprotonation of … See more Bisphosphonates Compounds containing 2 geminal phosphonate groups are known as bisphosphonates. They were first synthesized in 1897 by Von Baeyer and Hofmann and now form the basis for an important class of … See more In 1998 the consumption of phosphonates was 56,000 tons worldwide – 40,000 tons in the US, 15,000 tons in Europe and less than 800 tons in Japan. The demand of phosphonates grows steadily at 3% annually. Metal chelants See more Several methods exist for the preparation of phosphonic acids and their salts. From phosphonic acid Most processes … See more Hydrolysis Phosphonate esters are generally susceptible to hydrolysis under both acidic and basic conditions. Cleavage of the P-C bond is harder but can be achieved under aggressive conditions. O=PC(OR)2 + 2 H2O … See more Phosphonates are one of the three sources of phosphate intake in biological cells. The other two are inorganic phosphate and organophosphates. The naturally occurring phosphonate 2-aminoethylphosphonic acid was first identified in 1959 in … See more In medicine, phosphonates and bisphosphonates are commonly used as inhibitors of enzymes which utilize phosphates and … See more

Phosphonate - Wikiwand

WebWhat are Bisphosphonates? Bisphosphonates are a group of medicines that slow down or prevent bone loss, strengthening bones. Bisphosphonates inhibit osteoclasts which are responsible for breaking down and reabsorbing minerals such as calcium from bone (the process is known as bone resorption). WebHypophosphite, also known as phosphonate, is an ion. Its chemical formula is H 2 PO 2-. It contains phosphorus in its +1 oxidation state. It is made by disproportionation of … import photos as frames photoshop

List of Bisphosphonates - Drugs.com

WebPhosphonates or Phosphonic acids are organic compounds containing one or more C-PO (OH) 2 or C-PO (OR) 2 (with R= alkyl, aryl) groups. Bisphosphonates were first synthesized in 1897 by Von Baeyer and Hofmann. An example of such a bisphosphonate is HEDP. WebPhosphonates or Phosphonic acids are organic compounds containing one or more C-PO (OH) 2 or C-PO (OR) 2 (with R= alkyl, aryl) groups. Bisphosphonates were first synthesized … Webphosphonate (plural phosphonates) Any salt or ester of a phosphonic acid; many of its derivatives have important biological activity. Derived terms . acylphosphonate; … litery u