WebPrucalopride is used to treat chronic idiopathic constipation (CIC; difficult or infrequent passage of stools that lasts for 3 months or longer and is not caused by a disease or a … Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements. Prucalopride was approved for medical use in the … See more The primary measure of efficacy in the clinical trials is three or more spontaneous complete bowel movements per week; a secondary measure is an increase of at least one complete spontaneous bowel movement per … See more Prucalopride is contraindicated where there is hypersensitivity to the active substance or to any of the excipients, renal impairment requiring … See more Prucalopride, a first in class dihydro-benzofuran-carboxamide, is a selective, high affinity serotonin (5-HT4) receptor agonist with … See more In the European Economic Area, prucalopride was originally approved for the symptomatic treatment of chronic constipation in … See more Prucalopride has been given orally to ~2700 patients with chronic constipation in controlled clinical trials. The most frequently reported side effects are headache and gastrointestinal symptoms (abdominal pain, nausea or diarrhea). Such reactions occur … See more Prucalopride is rapidly absorbed (Cmax attained 2–3 hours after single 2 mg oral dose) and is extensively distributed. Metabolism is not the major route of elimination. In vitro, … See more • "Prucalopride". Drug Information Portal. U.S. National Library of Medicine. • "Prucalopride succinate". Drug Information Portal. U.S. … See more
Motegrity side effects and drug details - Inside Rx
WebMotegrity is a brand-name prescription medication used to treat chronic idiopathic constipation. The cause of this type of constipation is not known. This medication is … WebDec 14, 2024 · Generic Motegrity Availability. Last updated on Mar 9, 2024. Motegrity is a brand name of prucalopride, approved by the FDA in the following formulation(s): … bioshock remastered subtitles
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