Elf5-cre

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August undefined, 2024

WebMar 13, 2024 · For this purpose, we generate a transgenic mouse with the Cre recombinase inserted into the endogenous locus of Elf5 gene that is expressed specifically in … WebTherefore, in mice (Elf5-Cre knock-in), the expression of Cre recombinase driven by the Elf5 promoter can be used to study genes specifically and efficiently in the trophoblast lineage during ...

Epigenetic restriction of embryonic cell lineage fate by ... - Nature

WebElf5 knockout mice are embryonically lethal, limiting in vivo studies pertaining to its function. Moreover, haploinsufficiency of Elf5 limits the use of current mouse models to … WebApr 1, 2024 · Neonatal mouse kidneys deficient for Elf5 expression (Cdh16->Cre; Elf5*/f, where *= floxed or null allele) express 25% less Aqp2 and 25% less Avpr2 compared … margie mckevitt bucks county

Elf 5e (5th Edition) Race Full Guide in DnD Races

http://www.informatics.jax.org/recombinase/specificity?id=MGI:3811269&system=renal+%26+urinary+system WebApr 19, 2024 · Tumors overproducing PTHrP also displayed increased expression of nuclear pSTAT5 and Elf5, increased expression of markers of secretory differentiation and milk constituents, and histologically resembled secretory carcinomas of the breast. ... MMTV-Cre (Jackson Laboratories) and PTH1R fl/fl mice (from Henry Kronenberg, Boston, MA) ... WebCD51 + CD61 (Integrin alpha V + Integrin beta 3) CD51 / Integrin alpha V. CD52 margie mitchell lakewood ca

Generation of Elf5-Cre knockin mouse strain for trophoblast ... - PubMed

ELF5 inhibits the proliferation and invasion of breast …

WebGenerally taller than humans, elves possess a graceful, slender physique that is accentuated by their long, pointed ears. It is a mistake, however, to consider them weak … WebMar 21, 2024 · ELF5 (E74 Like ETS Transcription Factor 5) is a Protein Coding gene. Diseases associated with ELF5 include Down Syndrome and Haemophilus … margie mays song of the islandsWebThe Elf5-null mice have been described previously [14]. Mice of C57BL/6 strain (6–8 generations) were used for experi-ments with virgin mammary glands. The genotype of the con-trol wild-type (WT) animals was either K14-Cre/Elf5þ/þ or Elf5f/f, whereas the genotype of the Elf5 conditional knock-outs (Elf5-null) was K14-Cre/Elf5f/f. Animal ... margie meshew\u0027s thai on the table classes

"WebJun 19, 2024 · E74-like factor five (ELF5) is a basic transcription factor that plays a key role in breast tissue and gland development. However, the molecular mechanism of ELF5 in … " - Elf5-cre

Elf5-cre

Elf5 Regulates Mammary Gland Stem/Progenitor Cell Fate by …

WebOct 21, 2012 · The genotype of the control WT animals was either K14-Cre/Elf5 +/+ or Elf5 f/f whereas Elf5 conditional knockouts (referred to as Elf5-KO) were K14-Cre/Elf5 f/f. Animal procedures were conducted ... WebATP6V1B1 Antibody (PA5-56878) in ICC/IF. Immunofluorescence analysis of V-ATPase B1 was performed using 70% confluent log phase HaCaT and BeWo cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 45 minutes at room temperature.

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http://www.informatics.jax.org/recombinase/specificity?id=MGI:3699244&system=reproductive+system

WebThe transcription factor E74-like factor 5 (Elf5) functions downstream of the prolactin receptor signaling pathway and plays an important role in mammary gland development. Using conditional mouse knockouts, we have previously shown that Elf5-null mammary glands exhibit a complete failure of alveolo … WebAug 15, 2024 · The transcription factor ELF5 (ELF5) shows robust and directionally consistent associations across different outcome definitions, including a >4-fold higher risk (odds ratio: 4.88; 95%-CI: 2.47-9.63; p-value < 5.0 × 10 -6) for severe COVID-19 per 1 s.d. higher genetically predicted plasma ELF5. We show that ELF5 is specifically expressed …

WebMar 28, 2024 · Tg (Elf5-cre/ERT2,-GFP)2Rcha. Mutation details : A partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt … http://www.rpb.ioz.cas.cn/yjz/wangyanling/

WebOct 3, 2024 · The ablation of Sirt1 protein in Elf5 cre/+, Sirt1 fl/fl mice was first confirmed by IF staining (Figure 5b), and western blotting indicated that compared with those in the placentas of Sirt1 fl/fl littermates, in addition to increased acetylation of P53, the levels of both the P53 and P21 proteins were increased in Elf5 cre/+, Sirt1 fl/fl ...

WebMar 1, 2007 · To analyze the specificity and efficiency of Cre recombinase activity in Elf5-Cre mice, we mated Elf5-Cre mice with Rosa26mT/mGreporter mice, and found that Elf5-Cre transgene is expressed ... margie miller in north glenn cohttp://genesdev.cshlp.org/content/23/20/2382.full margie melody st theresa\u0027s academy 1976WebHomozygous null mice display embryonic lethality. Embryos homozygous for one null allele failed to develop extraembryonic ectoderm, did not maintain trophoblast stem cells, and had abnormal or absent mesoderm. Mice heterozygous for another allele had impaired lactation and mammary gland development. Gene Ontology. (GO) margie melody st theresa\\u0027s academy 1976