WebCreatine monohydrate supplementation enhances a variety of factors and processes involved in adaptation to exercise, including increased gene/ growth factor expression, satellite cell number and intracellular water content. ... In meta-analysis reviews, Lahners and colleagues (2015; 2024) also showed that creatine ingestion increases muscle ... Creatine is an amino acid located mostly in your body's muscles as well as in the brain. Most people get creatine through seafood and red meat — though at levels far below those found in synthetically made … See more Possible interactions include: 1. Caffeine.Combining caffeine with creatine might decrease the efficacy of creatine. Use of creatine with a daily amount of caffeine greater than 300 milligrams might also worsen the … See more Research on creatine use for specific activities and conditions shows: 1. Strength, muscle size and performance.Oral creatine use might allow an athlete to do more … See more When used orally at appropriate doses, creatine is likely safe to take for up to five years. As with any dietary supplement, it's important to choose a product that follows recommended … See more

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