Circeif4g3
WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ … WebCircEIF4G3 destabilizes δ-catenin protein by enhancing TRIM25-mediated ubiquitin degradation and functions as a miRNA sponge to modulate miR-4449/SIK1 axis, which synergistically leads to the ...
Circeif4g3
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WebDec 13, 2024 · Gastric cancer (GC) is the third most common cause of cancer-related death worldwide. Advanced diagnosis and high rates of relapse and metastasis are associated with the poor prognosis of this disease. GC has a complex etiopathogenesis of which the underlying mechanisms remain to be explored. WebAug 26, 2024 · Circular EIF4G3 (CircEIF4G3; hSA_CIRC_0007991) is downregulated in gastric cancer tissues and is associated with poor clinical prognosis. Overexpression of …
Web(A) Cell counting assays for control and circEIF4G3 overexpressing GC cells. (B) The impact of circEIF4G3 overexpression on GC cell proliferation was determined by cell colony formation assay. WebNov 16, 2024 · Overexpressing SRRM4, known for regulating ME inclusion in mRNAs critical for neural differentiation, in human HEK293 cells resulted in the biogenesis of …
WebFeb 2, 2024 · Renal cell carcinoma (RCC) is one of the top ten tumors over the world. RCC is not sensitive to radiotherapy and chemotherapy. Therefore, it is necessary to find new targets for the treatment. CircRNAs are a special type of noncoding RNAs, which play important roles in many types of cancer. In this study, we found circ_000558 was …
WebCircEIF4G3 destabilizes δ-catenin protein and inactivates β-catenin signaling. (A) TRAP experiment and LC-MS/MS analysis. GST protein expression was detected by western blot. δ-catenin protein...
WebAug 22, 2024 · This study found that CircEIF4G3 was down-regulated in gastric cancer patients and predicted poor prognosis. CircEIF4G3 destabilizes δ-catenin by forming a … christiana\\u0027s story john bunyanWebcells Article SRRM4 Expands the Repertoire of Circular RNAs by Regulating Microexon Inclusion Vanessa M. Conn 1,2, Marta Gabryelska 1,2, Shashikanth Marri 1,2, Brett W. Stringer 1,2,3, Rebecca J. Ormsby 1,2, Timothy Penn 1,2, Santosh Poonnoose 2,4, Ganessan Kichenadasse 2,5 and Simon J. Conn 1,2,* 1 Flinders Cancer Research, … george magazine collection to buyWebOct 19, 2024 · CDR1as expression is known to be correlated with hepatic microvascular invasion in HCC tissue and hsa_circ_0000520 (circRPPH1), hsa_circ_0005075 (circEIF4G3), hsa_circ_0066444 (circADAMTS9), and hsa_circ_0001649 (circSRPRH) have all been shown to be expressed at different levels in HCC compared to adjacent normal … george magnetic eyewearWebBackground: Circular RNAs (circRNAs), a new group of endogenous non-coding RNAs, plays a crucial role in various types of carcinomas. However, there is still limited … george maguire and michael john mcgannWebCircEIF4G3 acts as a scaffold to promote δ-catenin ubiquitin degradation by TRIM25. (A) The expression of δ-catenin protein in GC cells with or without circEIF4G3 overexpression after treatment... george maharis actor marriedWebBiogenesis Inc me circrna biogenesis factor Me Circrna Biogenesis Factor, supplied by Biogenesis Inc, used in various techniques. Bioz Stars score: 92/100, based on 3 PubMed citations. christian aubryWebNov 16, 2024 · We show here that ME-circEIF4G3 is controlled by SRRM4 and, given the down-regulation of SRRM4 in gliomas and association with poor survival outcomes, this … george magazine first cover